top of page
jetLOGO_edited_edited.png
IL2 effector OT1 ER tracker image 3 fixed zoom crop 5 um scale bar 2.png

We are currently accepting graduate students and postdocs to join our lab.

To learn more about our available postdoc position, click here. To apply, click here.

Please contact us if you are interested in joining our team.

IL2 sec61 image D zoom crop 5um scale bar.png

Thaxton Lab wins Paper of the Year in the Department of Cell Biology & Physiology at UNC Chapel Hill

unclinebergerbluev.jpeg

Thaxton lab receives Lineberger Comprehensive Cancer Center Tier 2 Innovation Award in collaboration with the lab of Johnathan Serody, MD to study protein stress in CAR T cells

Snip20230106_1.png

Brian Riesenberg's paper titled "Stress-Mediated Attenuation of Translation Undermines T-cell Activity in Cancer" accepted in Cancer Research, December 2022

er mito image.png

Check out the latest article from UNC Health Newsroom about the Thaxton Lab's latest endeavors studying cancer immunotherapy!

R37-merit-award-graphic-article.jpeg

The lab of Dr. Jennifer Guerriero's recent R01 award has been promoted to an R37 MERIT award. Congratulations to her team on this tremendous accomplishment!

logo_fcell.png

Congratulations to graduate student Ellie Hunt for the acceptance of her paper titled "The ER-mitochondria Interface as a Dynamic Hub for T Cell Efficacy in Solid Tumors" in Frontiers in Cell and Developmental Biology!

Evelyn_edited.jpg

Welcome Evelyn!

Evelyn Gandy graduated UNC in May 2022 where she majored in Psychology and minored in Biology and Chemistry while volunteering in the Thaxton Lab. We are excited that she has recently joined our team full-time as a Research Technician!

marsico_edited.jpg

The Thaxton lab has joined the University of North Carolina at Chapel Hill!

We are excited to join the team of dedicated researchers in the cancer immunotherapy group in Marsico Hall.

Wallace fig.png

A big congratulations to Dr. Kristen Wallace for her recent publication in Cancer Prevention Research titled "Immune Responses Vary in Preinvasive Colorectal Lesions by Tumor Location and Histology."

Click here to read more about Dr. Wallace's figure that made it on to the cover of this issue!

Guillermo pub2.png
Guillermo pub_edited.png

Congratulations to Guillermo Rangle-Rivera, PhD candidate, on his recent publication titled "Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy" in Frontiers in Immunology!

Aubrey pub.png
Aubrey pub2.png

Aubrey Smith, PhD candidate, has a paper in press in the Journal for Immunotherapy of Cancer titled "B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity." Congratulations Aubrey!

guerriero pub.png
Guerierro nat can_edited.png

Congratulations to the lab of Dr. Jennifer Guerriero on publishing their paper in Nature Cancer titled "Targeting Immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer"!

NCI_Stacked_COLOR.png
cancer-moonshot-logo_edited.jpg

Two R01 grants have been awarded by NCI/NIH to the Thaxton lab in 2020 as part of  the Cancer Moonshot Initiative on Immunometabolism!

1RO1CA348359-010: 4/01/2020 - 03/31/2025

Exploitation of ER Stress Induced Immune Dysfunction to Improve Cancer Immunotherapy

​

1R01CA244361-01A1: 7/1/2020 - 6/30/2025

Targeting Chronic ER Stress in T-Cells to Improve Cancer Immunotherapy

ER TR Low-0023 copy.jpg
IL2 Total-0053.jpg
IL15 Total-0029.jpg
ER TR Low-0019 copy.jpg
ER TR High-0009 copy.jpg
ER TR High-0020 copy.jpg
ER TR High-0004 copy.jpg
ER TR Low-0023 copy.jpg
IL2 Total-0053.jpg
IL15 Total-0029.jpg
ER TR Low-0019 copy.jpg
ER TR High-0009 copy.jpg
ER TR High-0020 copy.jpg
ER TR High-0004 copy.jpg
ER TR Low-0023 copy.jpg
IL2 Total-0053.jpg
bottom of page