The Thaxton lab has been awarded their first R01!
1RO1CA348359-010 has been awarded by the NCI/NIH for 4/01/2020 - 03/31/2025 as a part of the Cancer Moonshot Initiative on Immunometabolism
Title: Exploitation of ER Stress Induced Immune Dysfunction to Improve Cancer Immunotherapy
This work will study the role of ER stress sensor PERK to control CD8 TIL metabolism and antitumor immunity.
The Thaxton lab has received the MUSC Foundation for Research Development Award for 02/01/2020 – 01/31/2021
Title: Development of Novel Inhibitors to Target Cell Stress Response
The major goal of this project is to use medicinal chemistry to generate inhibitors that target the cell stress response in immune cells.
Dr. Thaxton gives an oral presentation at the Hollings Cancer Center Cancer Biology & Cancer Immunology Research Retreat where she shares her lab's most recent discoveries about T cell translation under stress
Dr. Thaxton sits down with Charleston local Cokie Berenyi for an episode of Perfect Day Podcast where they discuss cancer immunology research and what is on the horizon in novel cancer immunotherapies.
Dr. Thaxton's team SITCure wins Sparkathon!
Dr. Thaxton gives oral presentation on ER stress in TILs at SITC annual meeting
Kiley Lawrence wins an award at MUSC Student Research Day!
The Thaxton Lab's first paper has been published!
Endoplasmic reticulum stress contributes to mitochondrial exhaustion of T cells.
Hurst, KE, Lawrence, KA, Essman, MT, Walton, ZJ, Leddy, LR, Thaxton, JE.
Cancer Immunol Res. March 2018.