Thaxton Lab wins Paper of the Year in the Department of Cell Biology & Physiology at UNC Chapel Hill
Thaxton lab receives Lineberger Comprehensive Cancer Center Tier 2 Innovation Award in collaboration with the lab of Johnathan Serody, MD to study protein stress in CAR T cells
Brian Riesenberg's paper titled "Stress-Mediated Attenuation of Translation Undermines T-cell Activity in Cancer" accepted in Cancer Research, December 2022
Check out the latest article from UNC Health Newsroom about the Thaxton Lab's latest endeavors studying cancer immunotherapy!
The lab of Dr. Jennifer Guerriero's recent R01 award has been promoted to an R37 MERIT award. Congratulations to her team on this tremendous accomplishment!
Congratulations to graduate student Ellie Hunt for the acceptance of her paper titled "The ER-mitochondria Interface as a Dynamic Hub for T Cell Efficacy in Solid Tumors" in Frontiers in Cell and Developmental Biology!
Evelyn Gandy graduated UNC in May 2022 where she majored in Psychology and minored in Biology and Chemistry while volunteering in the Thaxton Lab. We are excited that she has recently joined our team full-time as a Research Technician!
The Thaxton lab has joined the University of North Carolina at Chapel Hill!
We are excited to join the team of dedicated researchers in the cancer immunotherapy group in Marsico Hall.
A big congratulations to Dr. Kristen Wallace for her recent publication in Cancer Prevention Research titled "Immune Responses Vary in Preinvasive Colorectal Lesions by Tumor Location and Histology."
Click here to read more about Dr. Wallace's figure that made it on to the cover of this issue!
Congratulations to Guillermo Rangle-Rivera, PhD candidate, on his recent publication titled "Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy" in Frontiers in Immunology!
Aubrey Smith, PhD candidate, has a paper in press in the Journal for Immunotherapy of Cancer titled "B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity." Congratulations Aubrey!
Congratulations to the lab of Dr. Jennifer Guerriero on publishing their paper in Nature Cancer titled "Targeting Immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer"!
Two R01 grants have been awarded by NCI/NIH to the Thaxton lab in 2020 as part of the Cancer Moonshot Initiative on Immunometabolism!
1RO1CA348359-010: 4/01/2020 - 03/31/2025
Exploitation of ER Stress Induced Immune Dysfunction to Improve Cancer Immunotherapy
1R01CA244361-01A1: 7/1/2020 - 6/30/2025
Targeting Chronic ER Stress in T-Cells to Improve Cancer Immunotherapy